Which of the following insulin types is known for its long duration and is not to be mixed with other types?

Insulin glargine (Lantus) is recognized for its long duration of action, typically lasting up to 24 hours. This makes it suitable for providing basal insulin coverage for patients with diabetes. The formulation of insulin glargine is distinct in that it is designed to release insulin steadily throughout the day, minimizing peaks and valleys in blood glucose levels.

One crucial aspect that sets insulin glargine apart from other types of insulin is its incompatibility with mixing. It cannot be combined with other insulin formulations in the same syringe due to changes in pH and potential precipitation, which can lead to unpredictable doses and compromised efficacy. This characteristic ensures that glargine maintains its intended effect and maintains stable glycemic control when administered as prescribed.

In contrast, other forms of insulin, such as regular insulin and NPH insulin, can be mixed in appropriate circumstances. Regular insulin has a quicker onset and shorter duration, while NPH has an intermediate duration but can still be mixed with regular insulin for a specific regimen. Insulin aspart is a rapid-acting insulin that is also eligible for mixing with other insulins.

By understanding the unique properties of insulin glargine, healthcare providers can tailor diabetes management effectively while ensuring patient safety through proper administration practices