Which condition is caused by excess cortisol production?

Study for the Dunphy Endocrine and Metabolic Problems Test. Engage with comprehensive questions and insightful explanations to prepare for your exam efficiently. Get exam-ready today!

The condition caused by excess cortisol production is Cushing's syndrome. This syndrome is characterized by an overabundance of cortisol in the body, which can arise from various factors, including pituitary adenomas that stimulate the adrenal glands, adrenal tumors, or ectopic ACTH production from other tumors. Symptoms associated with Cushing's syndrome include weight gain, particularly around the abdomen and face, thinning skin that bruises easily, hypertension, and glucose intolerance.

In contrast, hypothyroidism is related to insufficient production of thyroid hormones, Addison’s disease involves underproduction of adrenal hormones (including cortisol), and diabetes insipidus is related to the underproduction of antidiuretic hormone (ADH), leading to excessive urination. These conditions do not involve excess cortisol and therefore do not fit the context of the question.

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